![]() ![]() Murray and Nadel's Textbook of Respiratory Medicine, 5th ed. ^ Tietz NW (Ed): Clinical Guide to Laboratory Tests, 3rd ed."Transfusion-related acute lung injury: definition and review". ^ Toy P, Popovsky MA, Abraham E, Ambruso DR, Holness LG, Kopko PM, et al."FIO2 and acute respiratory distress syndrome definition during lung protective ventilation". ^ a b Allardet-Servent J, Forel JM, Roch A, Guervilly C, Chiche L, Castanier M, et al."Bench-to-bedside review: oxygen as a drug". "i stands for internet (and other things), not for inspired O 2 concentration". If the barometric pressure changes, the F IO 2 may remain constant while the partial pressure of oxygen changes with the change in barometric pressure.Įquations Abbreviated alveolar air equation P A O 2 = P E O 2 − P I O 2 V D V t 1 − V D V t References Often used in medicine, the F IO 2 is used to represent the percentage of oxygen participating in gas-exchange. F IO 2 is typically maintained below 0.5 even with mechanical ventilation, to avoid oxygen toxicity, but there are applications when up to 100% is routinely used. ![]() Oxygen-enriched air has a higher F IO 2 than 0.21 up to 1.00 which means 100% oxygen. Natural air includes 21% oxygen, which is equivalent to F IO 2 of 0.21. Medical patients experiencing difficulty breathing are provided with oxygen-enriched air, which means a higher-than-atmospheric F IO 2. ![]() Volumetric proportion of oxygen to other constituents in a breathing gasįraction of inspired oxygen ( F IO 2), correctly denoted with a capital I, is the molar or volumetric fraction of oxygen in the inhaled gas. ![]()
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